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Naloxone is used worldwide in medical emergencies to reverse respiratory depression caused by opioid overdose. It has no effect on non-opioid drug overdoses, no dependency potential and a high safety margin. Discovered and patented...

Cocaine is the hydrochloride salt produced from the leaves of the coca plant. Powder cocaine is typically snorted and less frequently injected. Crack is the smokable form of cocaine and is manufactured from...

Mental health problems are very common in those with a substance use disorder, and these patients have more clinically and psychosocially severe problems than patients with substance use disorders without comorbid mental...

Heroin is a semisynthetic opioid obtained by acetylation of morphine, which occurs as a natural product in opium: the dried latex of certain poppy species. Illicit heroin may be smoked or solubilised with...

Cannabis is the most widely consumed illicit drug in Europe. It has been used as a drug and a source of fibre since historical times. It is a natural product, the main psychoactive...